Estradiol Gel
$89.95 / MONTH
Perimenopause / Menopause relief, supports hormonal balance
*Your Effecty provider will help guide you to the best option based on your history, preferences, and symptoms. All prescriptions made only if deemed appropriate by the prescribing provider. Product image is for visual purposes only.
Product Details
Estradiol gel is a bioidentical, FDA-approved form of estrogen used to treat symptoms of perimenopause and menopause. It comes in easy-to-use single-dose packets you apply to your inner thigh daily. No pills, no hassle — just effective hormone therapy designed to help you feel like yourself again.
- Estradiol gel delivers transdermal estrogen directly through your skin.
- Apply to your inner thigh once a day — it absorbs quickly and dries in 2–5 minutes.
- The gel helps restore hormone balance, relieving menopause symptoms over time.*
- You may start to feel better in as little as 2–4 weeks, with full benefits typically within a few months.*
BENEFITS
- Bioidentical: Matches the estrogen your body naturally produces
- FDA-Approved: Safe, clinically proven, and widely prescribed
- Clean Ingredients: No dyes, peanut oil, or titanium dioxide—just pure, effective estrogen
- Mess-Free Application: Quick-drying gel, no odor once dry
- Consistent Dosing: Individually packaged for easy, on-the-go use
- Cardiovascular-Friendly: Transdermal estrogen is often a better fit for those with high blood pressure, diabetes, or clotting risks
- Whole-Body Relief: Eases hot flashes, mood swings, vaginal dryness, and more
Our clinical team will personalize your dosage and plan based on your medical history and symptoms.
EXPECTATIONS
Fewer hot flashes, better sleep, and fewer mood swings — all from a quick-drying gel that helps you feel like yourself again.
Do you need Progesterone too?
If you still have a uterus and you're taking systemic estrogen (like estradiol gel), progesterone is prescribed as well to help protect your uterine lining. We make it easy — oral progesterone is added for $19.95 / month to your treatment plan during your initial intake.
WHY ADD PROGESTERONE
- Protects your uterus: Estrogen alone can thicken the uterine lining over time, increasing your risk of endometrial cancer. Progesterone helps keep things balanced.
- Supports better sleep: Many people find progesterone has a calming effect and helps improve sleep quality.
- Eases anxiety + mood swings: It can help smooth out emotional ups and downs.
- Whole-hormone harmony: Estrogen and progesterone work best as a team, especially during menopause.
Feel like you again — science-backed HRT made simple and supportive.
Ask Us a Question, We're here to help!
Effecty offers Estradiol in two topical forms (a gel and a patch) and one oral form (a tablet). If you're starting Estradiol for the first time, one of the topical options is generally recommended.
- If you have sensitive skin or an allergy to adhesives, the gel may be your best choice.
- If not, it's mostly a matter of personal preference between the gel and the patch—both are effective.
- If you’ve previously been on Estradiol and were doing well with the oral tablet, you can continue with that form.
Your Effecty provider will help guide you to the best option based on your history, preferences, and symptoms.
Estradiol gel treats moderate to severe perimenopause and menopause symptoms like hot flashes, vaginal dryness, and mood swings. It’s also used to manage hormone levels in women at risk for osteoporosis or other estrogen-related health issues.
Just apply the full contents of one packet to your inner thigh once a day, at the same time each day. Let it dry before putting on clothes—usually in under 5 minutes.
We offer the following strengths:
- 0.25mg
- 0.5mg
- 0.75mg
- 1mg
- 1.25mg
If eligible, your Effecty provider will prescribe the best option based on your health history.
Yes! Estradiol gel is FDA-approved and bioidentical to the estrogen your body naturally makes.
If you still have a uterus and don’t already have a hormonal IUD, you’ll need to take oral progesterone alongside estradiol to prevent endometrial thickening.
We offer the following strengths: 100mg and 200mg.
If eligible, your Effecty provider will prescribe the best option based on your health history.
Most people begin to notice symptom relief in about 2–4 weeks, but full results may take up to 3 months. Consistency is key.
Absolutely. Fill out our online medical questionnaire, and a menopause-trained doctor will guide you to the best treatment for your symptoms and history.
